According to announcement of bureau of national intellectual property, environment of Lang Kun of Shenzhen city 301305/ > (301305) group Inc. applies for the name is “ the methodological “ of derv of biology of preparation of coupling of catalysis of a kind of lipase and strong acid colophony, make public date CN117568418A, application date is in November 2023. Patent summary shows, this invention belongs to biology the sources of energy and domain of organic synthesis technology, made public the method of derv of biology of preparation of coupling of catalysis of a kind of lipase and strong acid colophony. What narrate a method to be: In joining alcohol of feedstock oil and free lipase, short cable length reactor, 70 ℃ of 20 ～ issue catalytic response, get thick result; Classics of will crude production is centrifugal and detached, take distill of oily photograph decompression, get biology derv thick product; In joining biology derv thick product and alcohol of short cable length fill to cation exchanges the reactor of colophony activator, ester of 140 ℃ catalysis changes 40 ～ reaction, receive biology diesel oil. This invention mixes lipase catalysis two kinds of craft combine catalysis of strong acid colophony, between two workshop section join again with the decompression distill of semi-manufactured goods, can increase reaction efficiency and reaction stability. Undertake through using circumfluent reactor to reach pair of strong acid colophony further activation is handled, can increase catalytic efficiency and catalytic stability further, improve product quality.